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Sweet Syndrom (acute febrile neutrophilic dermatosis)

Sweet's Syndrom, or acute febrile neutrophilic dermatosis, is characterized by the presence of painful, reddened plaques on the face, extremities, and trunk. The syndrome is associated with acute leukemia in about 20% of patients, either myelocytic or myelomonocytic. Sweet’s syndrome may be induced by medications that stimulate neutrophil production, such as granulocyte colony-stimulating factor. Fever, a flulike illness, and arthralgias often accompany Sweet’s syndrome, which primarily affects women.


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