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Acromegaly

Acromegaly is a rare syndrome that occurs when the adenohypophysis secretes too much growth hormone (GH) even after the epiphyseal plates close during puberty. Arthropathy can be seen in up to 74% of affected patients. The knee joints, shoulders, hips, as well as the lumbosacral and cervical spine are the most common symptomatic areas - changes in the hands are particularly characteristic (e.g. soft tissue compaction, deformation of the epiphyses with quadratic enlarged terminal phalanges, chondrocalcinosis, enlarged joint/discal space).

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